e 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11137	(E)-GABAB receptor antagonist 1		GABA Receptor
	(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is ...		GABA Receptor
T9178	(E/Z)-GSK-3β inhibitor 1	GSK-3β inhibitor 1	GSK-3
	(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.		GSK-3
TN1159	(1(10)E,2R,4R)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one	[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one	Others
	(1(10)E,2R,4R)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one ([(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one) is a sesquiterpene from turmeric.		Others
T9307	(E)-3-(3,4-dichlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide		Others
	SR18662 a.k.a. SR18662 is a KLF5 inhibitor based on the optimized structure of ML264. It inhibits the growth of colorectal cancer in vitro and in vivo.		Others
TN2558	1-O-Deacetylkhayanolide E		Others
	1-O-Deacetylkhayanolide E is a natural product of Khaya, Meliaceae. The catalog number is TN2558 and the CAS number is 1007387-95-2. 1-O-Deacetylkhayanolide E can be used as a reference standard.		Others
T64359	Anti-inflammatory agent 36		Immunology/Inflammation related
	Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.		Immunology/Inflammation related
TN1555	Platycoside G1	Deapi-platycoside E	Others
	Platycoside G1 (Deapi-platycoside E) may have anti-inflammatory effects.		Others
T11175	Elenbecestat	E2609	Beta-Secretase , BACE
	Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.		Beta-Secretase , BACE
T15184	E 2012		Gamma-secretase
	E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induc...		Gamma-secretase
T18928	Brilliant Black BN	E 151	Others , Virus Protease
	Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A.		Others , Virus Protease
T4229	S1RA hydrochloride	E-52862 hydrochloride	Sigma receptor
	S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).		Sigma receptor
TN2557	1-O-Deacetyl-2alpha-hydroxykhayanolide E		Others
	1-O-Deacetyl-2alpha-hydroxykhayanolide E is a natural product of Swietenia, Meliaceae. The catalog number is TN2557 and the CAS number is 1189801-51-1. 1-O-Deacetyl-2alpha-hydroxykhayanolide E can be used as a reference ...		Others
T12090	Mogroside I E1		Others
	Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.		Others
T21853	(E)-AG 556		EGFR
	AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.		EGFR
TN2117	Pulsatilloside E	Pulchinenoside E	Others
	Pulsatilloside E (Pulchinenoside E) is a natural product isolated from the roots of Pulsatilla chinensis (Ranunculaceae).		Others
T1009	Estrone	Oestrone,Fluoroethyl,Aquacrine	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is pr...
T1986	Atopaxar	E5555,ER-172594-00	Protease-activated Receptor
	Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.		Protease-activated Receptor
T5155	(E)-AG 99	(E)-Tyrphostin AG 99,(E)-Tyrphostin 46,AG 99,Tyrphostin 46	EGFR
	(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).		EGFR
T1865	S1RA	E-52862	Sigma receptor
	S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (σ1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2 receptor (σ2R, Ki > 1000 nM).		Sigma receptor
T2681	HPGDS-IN-1		PGE Synthase
	hPGDS-IN-1 is a hPGDS inhibitor.		PGE Synthase